Role of NGF in OA Pain

Studies have identified a new key player in the transmission of pain associated with osteoarthritis (OA) in people, dogs and cats. In adults, Nerve Growth Factor (NGF) plays a significant role in pain signaling. Click on the link to watch the newly identified mechanism of action of Nerve Growth Factor in OA pain.

NGF in Osteoarthritis Pain

Duncan Lascelles, BSc, BVSc, PhD, FRCVS, CertVA, CertSAS, discusses the clinical implications of NGF for osteoarthritis pain.

NGF in Central Sensitization

Duncan Lascelles, BSc, BVSc, PhD, FRCVS, CertVA, CertSAS, discusses the clinical implications of NGF for central sensitization.

Anti-NGF for Control of Pain in Dogs and Cats

Read a paper published in Veterinary Record (January 5, 2019) that reviews the science behind NGF and the potential veterinary treatments based on this novel pathway by Masataka Enomoto, BVSc.

Feline Osteoarthritis

Canine Osteoarthritis

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Other Resources

Review Paper on anti-nerve growth factor monoclonal antibodies for the control of pain in dogs and cats.

The role of Nerve Growth Factor (NGF) in pain associated with osteoarthritis has been under investigation for the last two decades. In Dr. Enomoto’s review paper, the authors review the science behind NGF and the potential development of new pain treatments based on this novel pathway.

Published in the same journal, read the short review of the science behind the prior comprehensive article.

Measuring pain in dogs and cats using structured behavioural observation

Providing insight for veterinarians and pet owners alike, Dr. Reid’s recent review paper highlights the tools available to measure pain in dogs and cats based on behavioural changes.

Webinars

Could Nerve Growth Factor lead to a new era in Pain Management?