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about Sileo

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About Sileo

SILEO The name, pronounced /si-lehh-o/, is a Latin word meaning to “be silent.”


SILEO® (dexmedetomidine oromucosal gel) is an oromucosal gel formulation of dexmedetomidine hydrochloride provided in a 3ml syringe at a concentration of 0.1 mg/ml. Using the syringe, SILEO is easily administered between the cheek and gum, allowing for transmucosal absorption. Because SILEO is formulated to provide a low dose of dexmedetomidine, the dog remains calm, yet fully functional, and is able to interact normally with the family. 

Practical for Your Clients
Calming without sedating, allowing for normal dog-owner interactions
Easy to administer at home, when needed
► Can be used as part of an existing behaviour modification programme

Relief for Your Patients
Quick onset of action (Cmax 0.6 hrs)1
Supports early intervention for optimal effect on the quality of life of the dog2, 3

Confidence for You and Your Team
Proven to be effective in a randomised, placebo-controlled clinical trial
An innovative solution for a challenging condition
Comprehensive pet owner education resources




1.  Sileo 0.1mg/ml oromucosal gel SPC
2. Overall K. Manual of Clinical Behavioral Medicine for Dogs and Cats. St. Louis, MO: Elsevier-Mosby; 2013.

3. Tiira K, Lohi H. Reliability and validity of a questionnaire survey in canine anxiety research. Appl Anim Behav Sci. 2014;155:82-92.

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