Simparica: Efficacious against Sarcoptic mange
Dogs with natural infestations of Sarcoptes scabiei were given 2 monthly treatments of Simparica, as a result no mites were identified on skin scrapings in any of the dogs post treatment12.
Simparica aids in the rapid resolution of clinical signs of sarcoptic mange12.
Dogs with S.scabiei treated with 2 monthly treatments of Simparica12
| sarcoptic mange | ||||
|---|---|---|---|---|
| Clinical signs | % of dogs with clinical signs | |||
| Day 0 | Day 14 | Day 30 | Day 60 | |
| PRURITUS | 100% | 80.1% | 42.3% | 2.0% |
| ERYTHEMA | 96.2% | 75.5% | 38.5% | 5.9% |
| PAPULES | 94.3% | 60.4% | 30.8% | 2.0% |
| SCALING/ CRUSTING | 100% | 94.3% | 51.9% | 11.8% |
| ALOPECIA | 100% | 100% | 88.5% | 25.5% |
Simparica: Percentage of dogs with Demodex eggs in the skin scrapings14
In Simparica® treated dogs, no Demodex eggs were found after 90 days
Simparica: A single treatment with Simparica® is efficacious for the treatment in Otodectes cynotis13
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References:
1. Simparica SPC. 12. Becskei, C., De Bock, F., Illambas, J., Cherni, J.A., Fourie, J. J., Lane, M., Mahabir, S.P., Six, R. H., (2016) ‘E fficacy and safety of a novel oral isoxazoline, sarolaner (Simparica™), for the treatment of sarcoptic mange in dogs’ Vet. Parasitol. 222 pp. 56–61 13. Six, R.H., Becskei, C., Mazaleski, M.M., Fourie, J. J., Lane, M., Mahabir, S.P., Myers, M.R., Slootmans, N., (2016) ‘E fficacy of sarolaner, a novel oral isoxazoline, against two common mite infestations in dogs: Demodex spp. and Otodectes cynotis’ Vet. Parasitol. 222 pp. 62–66Zoetis Study A161C-XC-12-084.
